CONNECTS

Addressing a crisis of the magnitude and urgency of the COVID-19 pandemic transcends what any single entity can accomplish alone. It calls for the rapid and efficient mobilization and coordination of our nation's clinical trial infrastructure. The NHLBI Collaborating Network of Networks for Evaluating COVID-19 and Therapeutic Strategies (CONNECTS) was formed with the aim of helping prevent infection, slow or halt disease progression, and speed recovery... The CONNECTS model promotes seamless collaboration by fully integrating major NHLBI clinical trial networks under one organizational umbrella. An adaptive platform, master-protocol driven approach targets critical points along the clinical spectrum, from exposure to development of mild symptoms, to development of symptoms requiring hospitalization, and extending through convalescence and recovery.