Research efforts focus on (1) modeling signaling-to-transcription in macrophages using computational and experimental approaches, and (2) understanding mechanisms by which alveolar macrophages are programmed by the lung microenvironment. Our overall goal is to understand how macrophage signaling becomes dysregulated and the consequences for tissue homeostasis and inflammation...
First major grants for the lab! Funding our work related to modeling signaling-to-transcription networks (NIGMS R35) and lung-specific signaling (NHLBI R01). We are recruiting!...
The Gottschalk Lab in the Department of Immunology at the University of Pittsburgh investigates how cells process complex stimuli to inform appropriate immune function.