KHANLAB

We are working on computational tools to guide neurosurgeons towards more optimal resections, biopsies, and electrode implantations by extracting and exploiting the information present in medical images... Alterations in brain structure can be seen in many neurological disorders, both at the macro and the micro scale. We have been investigating sensitive techniques for quantifying brain structure using anatomical MRI morphometry techniques that are sensitive to the size and shape of the cortical and subcortical structures, and diffusion MRI to investigate microstructure... We are developing semi-automated pipelines for performing this image registration in applications that include temporal lobe resections, and carotid plaque endartarectomies, and are employing these tools to investigate the correlation between imaging and histological markers.