PROTEINQURE

ProteinQure is a computational platform for protein drug discovery. We partner with pharma to deliver experimentally validated novel chemical matter. We combine molecular simulations, machine learning and high performance computing algorithms to perform structure-based drug design. These physics based methods make us less dependent on large data sets... Proteins can target a wider range of binding sites compared to small molecules. We work on difficult targets including GPCRs and intracellular targets... Our partnerships involve wetlab validation and areas where data availability is often a challenge (GPCR and intracellular targets, non-natural amino acids etc.). We focus on novel peptides optimized for binding, specificity and other pharmacokinetic properties. In addition we engineer proteins to incorporate multiple binding domains. Our platform allows our partners to leverage their proprietary wetlab technologies to interrogate biology in new ways.

Also known as: ProteinQure Inc.

Primary location: Toronto Canada