MATRIX SCORE

The MATRIX Score was developed to predict the risk of crossover from radial access to femoral access among patients with acute coronary syndromes undergoing invasive management. The Risk Score is meant to assist operators in anticipating and potentially addressing difficulties in performing trans-radial procedures. The generation dataset consisted of 4197 patients assigned to radial access from the largest randomized trial comparing radial vs femoral access, the MATRIX trial. The Score was externally validated in 3451 and 491 patients assigned to radial access from the second-largest trial with randomized vascular access (RIVAL trial) and one of the largest randomized datasets focusing on STEMI (RIFLE-STEACS trial), respectively. Overall, 8139 patients from the derivation and validation cohorts were enrolled in 240 clinical sites from 33 countries worldwide.