WASHINGTON UNIVERSITY IN ST. LOUIS

Given the sheer size of the challenge, we use both computational and molecular technologies to predict and test the role of tyrosine phosphorylation on proteins and in cellular networks. Although we incorporate new mathematical and computational methods as needed to tackle the fundamental problems of our research, those techniques always have a foundation in statistical robustness. Hypotheses are tested in molecular and cellular systems, closing the loop between computation and experimentation... The Naegle lab seeks to understand the regulation and function of tyrosine phosphorylation in complex networks. Tyrosine phosphorylation is a protein...

Primary location: St Louis United States