TU LAB

The Tu Lab is investigating how a variety of cellular processes and decisions are coordinated with metabolic state, and how the dysregulation of these mechanisms might be linked to disease and aging... We are interested in deciphering the logic underlying epigenetic modifications on chromatin, the specification of gene expression programs, the regulation of translation in response to metabolic state, as well as core metabolic functions of TORC1 signaling and autophagy. We employ a variety of approaches including biochemistry, genetics, small molecule mass spectrometry, next-generation sequencing, imaging - whatever it takes - in our investigations. Guided by our findings, we are also keen on developing novel strategies for attacking particular cancers and other diseases linked to metabolism.

Primary location: Dallas United States