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Our approach revolves around change. Change is a fundamental aspect of nature. All things change over time. Stars grow or collapse. Rivers deepen or dry out. Populations grow or subside. Buildings decay. Cars traverse the landscape. Everything changes over time. A huge step in understanding nature was the development of a mathematics that describes change, and this was the calculus. Developed largely by Newton and Leibnitz, the calculus is used extensively in studies of the developing changes in nature. Extending the calculus, differential equations describe changes where parts of the system interact with each other as they change.</p... Institute for Systems Science @ DUT (ISS) Our laboratory, a small, dedicated group of mathematical scientists, develops differential equation models to understand various natural systems. The systems studied are quite varied, but the methods employed have synergies of approach. Prof. Duffy heads the group and is the South African National Research..