TOLTHEN XL

Presentation: Tolthen XL 4 mg prolonged-release capsules, hard. Indications: Symptomatic treatment of urge incontinence and/or increased urinary frequency and urgency as may occur in patients with overactive bladder syndrome. Dosage and Administration: Adults (including the elderly). The recommended dose is 4 mg once daily except in patients with impaired liver function or severely impaired renal function (GFR 30 mL/min) for whom the recommended dose is 2 mg once daily. In case of troublesome undesirable effects the dose may be reduced from 4 mg to 2 mg once daily. The effect of treatment should be re-evaluated after 2-3 months Paediatric population: The efficacy of tolterodine SR has not been demonstrated in children. Therefore, Tolthen XL is not recommended for children... In the 12 months to March 2021, the total cost to the NHS of prescribing Tolterodine XL, 2mg and 4mg, came to £10,572,438. The Tolthen price reduction can represent a saving to the NHS of £6,020,634 per annum.....

Primary location: Sedgefield United Kingdom