ZCSLAB.GITHUB.IO - Key Persons
Job Titles:
- High School Student Intern
Changlin Wan is a second year Ph.D. student in Electric Computer Engineering at Purdue University. Changlin joined BMDR in the fall of 2017. His primary research topic is developing new formulations of non-linear local low rank structure corresponding to gene co-regulation patterns in single cell RNA-seq data.
Dr. Yan Han is a master student in Biostatistics, IUSM. Her primary research topic is the modeling of the clinical trial data of Mek Inhibitor and Cabozantinib generated in the DHART SPORE.
Job Titles:
- Professor from Department of Computer Science
Dr. Yu Zhang is a visiting associated professor from Department of Computer Science, Jilin University. I collaborated with Dr. Zhang from 2015. Currently we have six co-authored manuscripts published or submitted. Dr. Zhang is primarily working on bioinformatics methods, computational tools, and algorithm and database development.
Job Titles:
- Member of the Lab Management Team
- Student
Job Titles:
- Member of the Lab Management Team
- Student
Job Titles:
- Member of the Lab Management Team
- Master Student
Kaman received her master degree in Clinical Oncology from Jinan University School of Medicine (Guangzhou, China) in 2016. Her research interest is using bioinformatic methods and clinical data to decipher cancers. Now she is a volunteer in Dr. Chi Zhang's Lab, working on several projects: (1) bioinforanalysis on Chr17p loss in TNBC and CRC; (2) cancer drugs' resistance mechanism.
Job Titles:
- Member of the Lab Management Team
- Master Student
Job Titles:
- Now a Postdoctoral Researcher at KAUST
Norah Alghamdi is a Ph.D. student in Bioinformatics at IUPUI. Norah is currently supported by a visiting scholar program of Saudi Arabia. Norah jointed BMDR in the November of 2018. Her first project is to study metabolic flux changes and oxidative stress in cancer.
Job Titles:
- Member of the Lab Management Team
- Master Student
Pengcheng Wang is a master student in Computer Science, IUPUI. He is working with Dr. Yu Zhang on several tool/database development projects.
Job Titles:
- Member of the Lab Management Team
- Student
Biography
Pengtao Dang received the B.E. degree in E-commerce from Qinghai University and M.S. degree in Software Engineering from Beijing Institute of Technology, respectively. He is currently a PhD student and a graduate research assistance in the School of Electrical and Computer Engineering, Purdue University, Indianapolis. His research interests are broadly at the algorithms, mathematical modeling and optimization, with a focus on applications in deep learning. In his personal life, he likes to watch movies, documentary, stand-up comedy and anime.
Sha Cao is highly motivated to pursue an academic career in bioinformatics and computational biology applied in translational sciences. My research tracks include: 1) development of novel statistical and machine learning techniques; and 2) addressing important translational and biological questions, through multiple omics data mining and quantitative modeling. Her current research focuses are:
Multiple omics data mining. This has been my main research focus, and the challenges we are dealing with include: how to effectively integrate multiple omics data types and enable knowledge transfer among them, locating latent structures within a dataset, and detecting locally homogeneous structures within the noisy background.
Cancer microenvironment and epigenetic regulation. Towards this goal, our specific aims are to understand: the regulatory effect of epigenome on transcriptome particularly regarding stress responses, and how the epigenome are aggregated in a way to cope with the cellular stresses.
Szuwei Du is a master student in Bioinformatics, IUPUI. He is working on development of an un-supervised method for mouse tissue data deconvolution.
Job Titles:
- Member of the Lab Management Team
- Student
Job Titles:
- Member of the Lab Management Team
- Student
Xiaoyu Lu is a second year Ph.D. student in Bioinformatics at IUPUI. Xiaoyu joined BMDR in the spring of 2018. I am co-advising Xiaoyu with Dr. Sha Cao from Biostatistics department. Xiaoyu is majorly mentored by Dr. Sha Cao. His research focus is to develop a semi-supervised deconvolution method to infer immune/hematopoietic cell proportions in the micro-environment of mouse bone marrow.
Job Titles:
- Member of the Lab Management Team
- Student
- Visiting Student
Biography
Xinyu Zhou received his bachelor's degree in computer Science and Technology from Changchun Institute of Technology in 2017 and his Master's degree in software Engineering from Jilin University in 2020. He is currently a PhD student and research assistant at the Luddy School of Informatics, Computing, and Engineering at Indiana University. His interests lie in algorithm design and mathematical modeling, and his research focuses on the intersection of bioinformatics and machine learning. In his daily life, Xinyu Zhou enjoys playing basketball, traveling and camping.
Xinyu Zhou is a visiting student from Department of Computer Science, Jilin University. Xinyu is officially a visiting Ph.D. student of my Ph.D. advisor-Dr. Ying Xu from the University of Georgia. Now Xinyu works in BMDR to develop method for tensor decomposition and knowledge graph embedding.
Yan Huo is a first year visiting Ph.D. student. She is funded by her college - China Medical University, one of the top ten medical schools in China. Yan jointed my lab in Oct 2018 for a one year study. Her current research project is to develop a computational method to predict most similar cancer cell line for a cancer bulk tissue sample by using RNA-seq data and genetic mutation data.
Job Titles:
- Member of the Lab Management Team
- Student
Biography
Yifan received his B.S. and M.S. from Jinan University (Guangzhou, China) and studied in Guangdong Province Key Laboratory of Molecular Immunology and Antibody Engineering for 5 years. He was well trained during this period and participated several projects mainly about: (1) Development of mAb-based sandwich ELISA kit for disease diagnosis, (2) Identification of major shellfish allergens and development of desensitizing vaccines, (3) Combinational effects of mAb drug and platinum drug on NSCLC in vitro and in vivo. Several papers were published and two patents were authorized. Now, Yifan is a Ph.D. candidate in IU school of medicine with great interests on chr17p loss in cancer and cancer immunotherapy. He is trying to incorporate computational methods to his bench work research, and he is developing a T cell-based CRISPR library screening to uncover genetic defects which may affect T cell activities in triple negative breast cancer and colorectal cancer.
Job Titles:
- Member of the Lab Management Team
- Master Student
Biography
Yue Fang received a Bachelor's degree in E-Commerce from Nankai University in 2014 and a Master's degree in Electronic Commerce and Logistics Technologies from The Chinese University of Hong Kong in 2015, respectively. She is currently studying in the master's program in Biostatistics Department, Indiana University. Her research interests are broadly at the applied statistics, machine learning and statistics model, with a focus on applications in Alzheimer's disease and cancer genomic data science. In her personal life, she loves reading and hiking.
Job Titles:
- Member of the Lab Management Team
- Visiting Scholar