ACTA2 ALLIANCE

Multisystemic Smooth Muscle Dysfunction Syndrome (MSMDS) is an ultra-rare disease in which there are less than 50 known cases worldwide. MSMDS affects all of the smooth muscle in the body and is considered to be multisystemic due to its ability to affect most of the subsystems in one's body. MSMDS is caused primarily by an ACTA2.R179H genetic mutation, however has been documented to be caused by ACTA2.R179C as well... Smooth muscle is the type of muscle that most internal organs like the bladder, the intestines, the uterus, the lungs and the vessels of the body use. Unlike the skeletal muscle in our body that control our movement, we have little voluntary control of the smooth muscle. The smooth muscle in the uterus, for example, helps a woman to push out her baby. In the bladder, smooth muscle helps to push out urine. Smooth muscle determines the flow of blood in the arteries and the blood pressure. Smooth muscles move food through the digestive tract. In the eye, smooth muscle..

Also known as: ACTA2 Alliance, Inc.

Primary location: United States