CSF biomarkers for the diagnosis and prognosis of Parkinson's disease: systematic review and IPD meta-analysis... Parkinson's disease (PD) is a progressive neurodegenerative disorder, its worldwide incidence is generally comprised between 10 and 50/100.000 person-years, and its prevalence between 100 and 300/100,000 population... Although imaging and ancillary investigations may be helpful in the diagnostic workup, the diagnosis of PD mostly relies on the clinician's expertise and molecular markers are not available.
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