DUKE STREET BIO - Key Persons


Dr Elliott Sigal

Job Titles:
  • Senior Advisor, New Enterprise Associates ​ Co - Chair SAB, Amgen ​ Former CSO, Bristol Myers Squibb

Dr Geert Maertens

Job Titles:
  • Co - Founder and Former / Chief Scientific Officer

Dr Rob Williams

Job Titles:
  • Chief Drug Development​ Scientist, CRUK

Dr Ronan O'Hagan

Job Titles:
  • CSO, Apricity Health Former Executive Director, Oncology Discovery

Dr. Alan Wise - CEO

Job Titles:
  • Chief Executive Officer

Dr. Barry McGuinness - COO

Job Titles:
  • Chief Operating Officer

Dr. Dónal Landers

Job Titles:
  • Chief Medical Officer
  • Physician
Dónal Landers is a highly experienced pharmaceutical physician with a proven track record of leading multiple molecules through early oncology clinical development. Dr Landers combines science, medicine with an entrepreneurial flair to drive translational and clinical drug development in oncology. After obtaining his primary medical degree from Trinity College, Dublin, Dónal spent several years practicing hospital clinical medicine. He undertook an MBA at University College Dublin before transitioning to senior management at St. James's Hospital. Dónal then co-founded his own health informatics company developing ‘patient-centric' mobile technology solutions, enabling patients to collect and monitor their own health data. Dónal was also co-founder and Strategic Director of the Digital Experimental Cancer Medicine Team based at Cancer Research UK Manchester Institute. This research team was setup to provide next generation patient cancer care using data-driven evidence to enable the transformation of clinical decision-making.

Dr. Jeff Thompson

Job Titles:
  • Head of Clinical Operations
Dr. Jeff Thompson, PhD, MBA brings a wealth of experience spanning over three decades in the Pharma and Biotech Industries, and has an impressive record of taking molecules from preclinical research through to clinical development. Jeff obtained his BSc in Biochemistry from Liverpool Polytechnic, followed by a PhD in Cell Biology/Biochemistry at Victoria University of Manchester. Further complementing his scientific background, Jeff completed an MBA at Henley Management College. Jeff most recently served as a Senior Director of Clinical Programs at AstraZeneca UK, where he successfully oversaw a portfolio of clinical studies for various oncology targets. Before AstraZeneca, he was the Vice President of Clinical Operations at Inflazome UK, where he led the operations to transition pre-clinical assets into clinical development. Under his leadership, Inflazome successfully navigated two assets through First in Human (FTIH) studies, contributing to the company's acquisition by Roche in 2021.

Dr. Phill Cowley

Job Titles:
  • Chief Scientific Officer

Peter Trill - Chairman

Job Titles:
  • Chairman

Prof Iain McNeish

Job Titles:
  • Professor of Oncology

Prof Jason Luke

Job Titles:
  • Director, Immunotherapy and Drug Development Center, UPMC Hillman Cancer Center and University of Pittsburgh

Prof Jason Matthews

Job Titles:
  • Professor, Department of Nutrition / University of Oslo, Department of Pharmacology & Toxicoloty / University of Toronto

Prof Nicola Curtin

Job Titles:
  • Professor of Experimental Cancer Therapeutics

Prof Ruth Plummer

Job Titles:
  • Professor of Experimental

Prof Timothy Yap

Job Titles:
  • Medical Director, Institute for Applied Cancer Science