CONTE CENTER FOR NEUROIMMUNE STUDIES CONTENT - Key Persons
Job Titles:
- Group Leader
- Research Scientist
- Investigator
Adam Granger is a group leader and research scientist in the Stanley Center for Psychiatric Research of the Broad Institute of MIT and Harvard, where he studies the molecular, cellular, and circuit mechanisms underlying neuropsychiatric disorders. His group is developing high-throughput methods for characterizing local and long-range brain circuits to identify convergent changes caused by gene mutations implicated in schizophrenia and bipolar disorder.
Prior to joining the Stanley Center, Granger completed his postdoctoral training in the lab of Bernardo Sabatini at Harvard Medical School, studying the synaptic connectivity of multi-transmitter neurons. He earned his Ph.D. in neuroscience from University of California, San Francisco carrying out his thesis research on the molecular mechanisms of synaptic plasticity. He also holds a B.A. in biology and mathematics from Kalamazoo College.
The Sabatini lab seeks to uncover the mechanisms of synapse and circuit plasticity that permit new behaviors to be learned and refined. We are interested in the developmental changes that occur after birth that make learning possible as well as in the circuit changes that are triggered by the process of learning. Lastly, we examine how perturbations of these processes contribute to human neuropsychiatric disorders such as Tuberous Sclerosis Complex and Parkinson's Disease.
Beth Stevens received her PhD in Neuroscience in 2003 from the University of Maryland, College Park and completed her postdoctoral fellowship at the Stanford University School of Medicine in 2008 in the lab of Ben Barres where she studied the roles of glia and complement system in synaptic refinement. She is an institute member of the Broad Institute, an associate professor at Harvard Medical School, and a research associate in neurobiology at Boston Children's Hospital.
Job Titles:
- Scientific Coordinator, Conte Center / Project Manager, Boston Children 's Hospital and Broad Institute of MIT and Harvard
Krishna Narayanan completed his PhD at the University of Illinois Urbana-Champaign under the mentorship of Drs. Erik Procko and Diwakar Shukla. He worked on understanding the structure to function relationships of transmembrane proteins, using high-throughput mutagenesis libraries coupled with flow cytometry and deep sequencing. In 2023, he joined the Stevens lab as a Project Manager to help drive projects and collaborations toward success and assist in legal and regulatory compliance. As the Scientific Coordinator for the Conte Center, he works with the scientists to facilitate meetings, update the website, and plan the biannual symposium.
Job Titles:
- Professor of Neurology and Neurological Sciences, Pediatrics, and Genetics
Matt completed his PhD at Yale in the lab of Nenad Sestan, working on gene expression patterns and molecular mechanisms influencing human cortical development. During postdoctoral training with Chris Walsh at Boston Children's, he continued to work on cortical stem cell diversity and functions using both human tissue and animal models, including mice and ferrets. As a staff scientist in the Stevens lab located within the Stanley Center at the Broad Institute, he coordinates and contributes to a number of collaborative, interdisciplinary projects focused on understanding the role of microglia and complement-mediated synaptic pruning in schizophrenia and other psychiatric disorders.
Michael Carroll received his Ph.D. in Immunology from the UT Southwestern Medical School (Dallas, TX) under the direction of Dr. J. Donald Capra in 1980; subsequently he trained with Dr. Rodney R. Porter in the Biochemistry Department, Oxford U (Oxford UK). In 1985, he was appointed an Assistant Professor in Pediatrics and the Department of Biological Chemistry at the Children's Hospital/Harvard Medical School. He was promoted in 1998 to the rank of Professor of Pediatrics, Harvard Medical School and Senior Investigator, Boston Children's Hospital, Program in Cellular and Molecular Medicine.