ONEPAGE

Specific interaction of small molecules with macromolecules is a fundamental phenomenon of all biological processes, from gene regulation to the fight against diseases. Our main motivation in the Laboratory of Molecular Design is to decipher the molecular code of protein-ligand interactions at an atomic level. Our group is at home in the areas of bioinformatics and cheminformatics, where we develop new computational methods for the prediction of molecular binding events. Our main research interest focuses on the area of ​​computational chemogenomics, which is an interdisciplinary research field that aims to predict ligand-protein interactions at the genome level with help of in silico approaches. The identification of the target profile of small, drug-like molecules is important for the discovery of new drugs, to flag off-targets, for the identification of new targets for known drugs (repositioning / drug repurposing) and to deorphanize ligands without known targets and receptors..

Primary location: Santiago Chile