MAIN STREET INN

Located in the heart of Sainte Genevieve's Historic District, and surrounded by beautiful wine country, we are just a short one-hour drive from both St. Louis and Cape Girardeau, five hours from Chicago and just a little over four hours from Nashville... Originally built in 1882, as the Meyer Hotel, the Main Street Inn B&B has long been considered one of Missouri's finest bed and breakfast establishments. Having undergone and completed an extensive renovation and reopening in 2017, the Main Street Inn B&B's proprietors, Susan O'Donnell and Patrick Fahey would like to welcome you to what we hope will be a truly wonderful, relaxing and memorable experience... Stay at our elegant and historic bed breakfast in the heart of beautiful Sainte Genevieve Missouri. Click to view book direct!

Primary location: Sainte Genevieve United States