CHAGASTOPE

Chagastope is an atlas of antigens and epitopes for Chagas disease. The resource contains experimental data on antibody-binding to millions of synthetic peptides. Data was obtained by assaying high-density peptide arrays with serum samples from Chagas Disease subjects and matched healthy donors across the Americas... We produced signal plots to visualize the antibody-binding signal (antigenicity) for peptides along proteins. This plots show the location of antigenic regions and epitopes in antigens. Static plots are PDFs with the same plots in the Chagas Antigen and Epitope Atlas paper. Dynamic plots are generated in real time from the data, and allow users to choose the serum samples (assays) to plot, change the scale of the plots, cutoff and tweak a few additional visualization options. Dynamic plots are also interactive, they are rendered by plotly and can be zoomed, rescaled, panned, and additional information can be displayed by moving the mouse cursor over data points. After..