DDI-PREDICTOR

DDI-Predictor is a website dedicated to quantitative prediction of the impact on drug exposure of drug-drug interactions mediated by cytochromes P450 3A4, 2D6, 2C9, 2C19 and 1A2, as well as genetic polymorphism of these cytochromes, the combined effect of drug interaction and cytochrome polymorphism, cirrhosis, and drug-drug interactions in cirrhotic patients... DDI-Predictor is NOT a database in the usual sense. DDI-Predictor is able to make quantitative predictions of drug exposure e.g. in case of drug-drug interaction even if this interaction has not been studied. This is the distinctive feature of DDI-Predictor. The predictions are made using static equations of physiologically-based pharmacokinetic models... DDI-Predictor is a drug drug interactions and pharmacogenetics checker