WESSELING-LAB.COM

We use molecular, cellular, genetic, live imaging, and electrophysiological techniques to study synaptic transmission in a variety of mammalian central nervous system synapses. We are mostly focused on the physiology of presynaptic terminals. We believe that a comprehensive theoretical understanding will be essential for figuring out the nature of information processing and storage in neuronal ganglia and brains throughout the animal kingdom because of a phenomenon termed frequency dynamics, or short-term synaptic plasticity that seems to be expressed, in one form or another, by the presynatic terminals of all chemical synapses... We are a small group, and we care a lot about good experimental design because we believe this gives us a better chance of thinking outside of the box when standard ideas come up short.