RAJBHANDARILABSINAI.ORG

Laboratory of Dr. Prashant Rajbhandari uses molecular biology, biochemistry, and genomic science to study lipid metabolism. Dr. Rajbhandari completed his doctoral studies at the University of Wisconsin-Madison where he elucidated how structural changes in the unstructured region of Estrogen Receptor-alpha increases its ligand-independent transcriptional function to promote drug-resistance in breast cancer. An intriguing relation between metabolism and cancer led him to his pursuit of postdoctoral studies in the Lab of Dr. Peter Tontonoz, MD PhD in the Howard Hughes Medical Institute (HHMI) at the University of California-Los Angeles (UCLA). At UCLA, his interests were broadly focused in understanding lipid metabolism, particularly in adipose tissues and how it affects adipocytes, hepatic, and cardiovascular function. He discovered immune-adipocyte crosstalk in the adipose microenvironment that function to limit mitochondrial respiration, energy expenditure, lipid mobilization and block..

Primary location: New York United States