WASHINGTON UNIVERSITY IN ST. LOUIS

Our lab is focused on understanding the mechanism by which roseoloviruses induce autoimmunity. We are also studying other thymotropic viruses to understand if viral disruption of immune regulation is specific to roseolovirus or might also occur after infection with other viruses. Finally, we are using immunologic tools and molecular virology to understand what long-term impact thymic infections have on immune cells, as well as host virus interactions that alter immunologic tolerance... We study how viruses disrupt the immune system and contribute to autoimmune disease. Millions of people suffer from autoimmunity and the prevalence c...

Also known as: Bigley Lab

Primary location: St. Louis United States