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Pancreatic islet - insulin secreting beta cells in green and glucagon secreting alpha cells in red. Research People Publications Contact Recently it has be come clear that diabetes is not only a disease of reduced insulin signalling and secretion, but a bi-hormonal disease where the hormone glucagon contributes to the pathologically high blood glucose levels.... Our research aims to understand how glucagon secretion is regulated, how alpha cells interact with the sorrounding environment and how changes in alpha cell function contribute to changes in glucose metabolism.