SCULPTING REGENERATION

Regenerative medicine offers significant promise to restore tissue functions from damage and to improve quality of life. Tissue damage often results in fibrosis and impaired organ function, which accounts for up to 45% of all deaths in the developed world. Despite an exponential growth in various approaches to regenerate tissues, clinical adoption has been limited due to incomplete mechanistic understanding and lack of control in cell functions. We are interested in understanding how cells build and remodel their environments in physiology and disease. Our team is pursuing multidisciplinary approaches to understand the fundamentals in physical biology of regenerative processes and to leverage these insights by precisely directing donor cells and modulating the host response to treat tissue injury, degeneration and fibrosis. Target organs include the bone marrow, bones, vasculature, and lungs... We are combining biomaterial design with microtechnologies to build instructive niches that..

Primary location: Chicago United States