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  • www.dacosta.net
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Evolved to convert chemical signals into electrical impulses, ligand-gated ion channels are Nature's ultimate molecular sensors, controlling fundamental physiological processes. The dacosta]:[lab seeks an atomic-level understanding of ligand-gated..
Relevance: 30.07463
  • moronilab.com
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Ion channels are membrane proteins that control cell electrical signals in response to a variety of physical and chemical stimuli. We study how stimuli are perceived and transduced at the molecular level in order to understand common gating..
Relevance: 26.000172
  • fas-ligand.com
Dephosphorylation of Fas-ligand and caveolin-1 is a prerequisite step in Fas-ligand - caveolin-1 complex formation and cell death stimulation... Human intrahepatic regulatory T cells are functional, require IL-2 from effector cells for survival, and..
Relevance: 19.061419
  • www.biomoltech.com
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Lead Finder is a leading software for virtual screening of candidate drug molecules and quantitative evaluation of interaction between protein and ligand molecules. Lead Finder ranks ligands by their predicted biological activity, determines 3D..
Relevance: 17.850681
  • www.dockingserver.com
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DockingServer offers a web-based, easy to use interface that handles all aspects of molecular docking from ligand and protein set-up... While its user friendly interface enables docking calculation and results evaluation carried out by researchers..
Relevance: 17.472015
  • 3d-e-chem.github.io
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Virtual machine with all software and sample data to run 3D-e-Chem KNIME workflows... This project will develop technologies to improve the integration of ligand and protein data for structure-based prediction of protein-ligand selectivity and..
Relevance: 17.44438
  • biocircuits.github.io
13. Promiscuous receptor-ligand interactions increase the bandwidth and specificity of cell-cell communication systems..
Relevance: 16.83853
  • modsim-pharma.com
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MODSIM Pharma was founded in late 2018 as a spin-off from Uppsala University, with the support of the Uppsala Innovation Office. After some incubation period, the company is reaching the market with innovative solutions to characterize protein ligand..
Relevance: 16.496702
  • www.cadd2drug.org
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The activation of GPCRs involes in the molecular switches of protein residue sidechains. A continuous water channel forms upon the activation... GPCRs, encoded by 826 different genes in the human genome, are the most important targets for modern..
Relevance: 16.288212
  • www.confgen.net
Small-molecule (ligand) conformer generation is usually performed prior to protein-ligand docking. RDKit [1] uses the ETKDG method to generate a collection of diverse low-energy conformers. Generation may take a while depending on how many conformers..
Relevance: 15.962198
  • www.cellchat.org
CellChat Explorer contains two major components: (a) Ligand-Receptor Interaction Explorer that allows easy exploration of our ligand-receptor interaction database, and (b) Cell- Cell Communication Atlas Explorer that allows easy exploration of the..
Relevance: 15.905642
  • mscottfsi2013.weebly.com
The Characterization of Metal Acetate Salts (Zinc and Copper) with 2-(methylthio)-N-(3-pyridinylmethyl) acetamide (3-HLSMe) and 2-(methylthio)-N-(4-pyridinylmethyl) acetamide (4-HLSMe)... A coordination polymer is a compound consisting of a ligand..
Relevance: 15.601252
  • hla-ligand-atlas.org
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The HLA Ligand Atlas is a comprehensive collection of tissue and HLA allele specific HLA ligands that are naturally presented. The data was generated in standardized mass spectrometry experiments and analyzed using a well defined computational..
Relevance: 15.504415
  • www.memgenbio.com
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Memgen is clinically testing its lead viral immunotherapy MEM-288 for advanced non-small cell lung cancer (NSCLC). MEM-288 combines our proprietary CD40 ligand with interferon beta (IFNβ) to provide the optimum capability to generate a robust, whole-..
Relevance: 15.289544
  • www.swissbioquant.com
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Swiss BioQuant is a bioanalytical contract research organization (CRO) specialized in LC-MS/MS and ligand-binding assays and dedicated to scientific excellence. With a deep understanding of customer requirements, Swiss BioQuant is the bioanalytical..
Relevance: 15.17914
  • www.theclarklab.com
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The Clark Group engages in new reaction discovery to enable the synthesis of novel pharmaceuticals and natural products. At the core of our research program is the development of selective transition metal-catalyzed reactions. Researchers will be..
Relevance: 15.035198
  • www.aquamem.com
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Discovery and de-novo design of small-molecule antimicrobials targeting human, animal and plant pathogens. We offer comprehensive solutions, including target selection, bioinformatics, homology modeling and virtual ligand screening...
Relevance: 15.0307455
  • clarkresearchgroup.org
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In the Clark Research Group, our projects capitalize on ligand influence in transition metal complexes for the purpose of: (1) creating new functional materials, (2) facilitating new reactivity, and (3) controlling and expanding known reactivity...
Relevance: 14.944899
  • www.ibodies.eu
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iBodies®, the novel macromolecules designed to fully substitute antibodies in common biochemical methods, are now ready for routine use in laboratories. iBodies® were successfully tested in ELISA, flow cytometry, confocal microscopy, Western..
Relevance: 14.901496
  • www.q-mol.com
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Q-MOL L.L.C. provides research and development services in the field of in silico structure based rational drug desing and discovery... At Q-MOL L.L.C. we believe we have solved the problem of protein-ligand docking. Realizing that this might sound..
Relevance: 14.822529
  • www.planetbiotechnology.com
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Planet Biotechnology produced the first plant-made antibody, or "plantibody", ever tested in a clinical trial. We are focused on discovering, developing and commercializing new antibody-based therapeutic and preventative products through cultivation..
Relevance: 14.689535
  • www.promys.eu
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The global chemical industry is transitioning from petrochemical production processes to bio-based production processes. This transition creates a clear market need for technologies that reduce the development time and cost of cell factories. PROMYS..
Relevance: 14.57464
  • drugsniffer.org
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Drug Sniffer is a virtual screening (VS) pipeline capable of screening billions of molecules using only thousands of CPU hours, using a novel combination of ligand-based (LBVS) and structure-based (SBVS) methods...
Relevance: 14.569532
  • www.axuus.com
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Axuus offers virtual solutions for gated and non-gated communities, apartments, and commericial buildings. Services include live help, access control, tracking license plates, camera recording, maintenance and more!... Axuus offers a wide variety of..
Relevance: 14.526011
  • web.natur.cuni.cz
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We strive to gain a better mechanistic insight into the processes co-regulated by direct protein-protein interaction between components of Notch and Wnt pathways and Non-canonical Notch-ligand mediated signaling in development, homeostasis and..
Relevance: 14.244718
  • www.prosarx.com
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ProsaRx is the in silico/computational unit within RxCelerate via acquisition of Prosarix in 2019. RxCelerate was founded in 2013 with a vision to provide a bespoke high quality outsourced drug discovery and development platform. Originally focused..
Relevance: 14.157319
  • www.skdconsultingllc.com
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SK D Consulting LLC offers biophysical consulting services for the measurement of the binding kinetics and equilibrium dissociation constants of protein/protein or protein/ligand interactions by various biosensor and KinExA (Kinetic Exclusion Assay)..
Relevance: 14.120195
  • www.icdrug.com
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This module is used to calculate the binding energy of proteins and small molecules or complexes between proteins and proteins, using molecular dynamics simulation, alanine scanning, interaction entropy and other technical principles to determine hot..
Relevance: 14.043794
  • www.blacksandtherapeutics.com
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Blacksand Therapeutics is a London-based startup biotech that is focused on using a multifactorial AI approach to integrate phenotypic and neurochemical profiles with ligand overlays to discover and develop a new class of precision therapeutics for..
Relevance: 13.858515
  • www.iontosorb.cz
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IONTOSORB ® is a private company since 1991. We produce sorbents based on macroporous Bead Cellulose (Macroporous Sorbents for Bioseparations, Ion Exchange, Affinity and Dye-Ligand Chromatography, Chelating (Selective) Sorbents, IMAC and Sorbents for..
Relevance: 13.782439