IBODIES

iBodies®, the novel macromolecules designed to fully substitute antibodies in common biochemical methods, are now ready for routine use in laboratories. iBodies® were successfully tested in ELISA, flow cytometry, confocal microscopy, Western Blotting, protein immobilization and immunoprecipitation methods. These fully synthetic antibody mimetics consist of N-(2-hydroxypropyl) methacrylamide (HPMA) copolymer backbone decorated with low-molecular-weight functional groups: a targeting ligand, an affinity anchor and an imaging probe (Fig.1). In theory, iBodies® can be custom designed towards any protein of interest (provided a ligand is known) and tailored based on the intended applications... + Flexible platform (the type and number of functional groups per iBody molecule is adjustable)

Primary location: Prague 6 Czech Republic