IL-13

Several Th2 cytokines, including IL-13, are key drivers of inflammation in atopic dermatitis. 2-4... Th2 cytokines, including IL-13, are key drivers of inflammation in atopic dermatitis. IL-13 causes increased inflammation, disruption of the skin barrier, and a persistent itch on affected areas... Th2 cytokines such as IL-4 and IL-13 play key roles in the inflammation underlying AD signs and symptoms. In AD skin, overexpression of IL-13 leads to a variety of pathophysiologic issues, including disruption of the skin barrier and amplified inflammation. 4, 9-15

Primary location: Lier Belgium